Menahydroquinone-4 may play a key role in regulating CCL5 expression induced by epidermal growth factor receptor inhibitors

Abstract Epidermal growth factor receptor (EGFR) inhibitors frequently cause severe skin rash as a side effect, which is a critical burden for patients who continuously receive drug treatments. Several recent clinical trials have shown that vitamin K is effective against these side effects; however,...

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Bibliographic Details
Main Authors: Shotaro Goto, Shuichi Setoguchi, Daisuke Watase, Hirofumi Yamakawa, Ayano Yamada, Mitsuhisa Koga, Koichi Matsuo, Kazuhisa Matsunaga, Yoshiharu Karube, Jiro Takata
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-49627-8