Knocking down AR promotes osteoblasts to recruit prostate cancer cells by altering exosomal circ-DHPS/miR-214-3p/CCL5 pathway

Knocking down AR promotes osteoblasts to recruit prostate cancer cells by altering exosomal circ-DHPS/miR-214-3p/CCL5 pathway

Tumor-derived exosomes have been shown to play a key role in organ-specific metastasis, and the androgen receptor regulates prostate cancer (PCa) progression. It is unclear whether the androgen receptor regulates the recruitment of prostate cancer cells to the bone microenvironment, even bone metast...

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Bibliographic Details
Main Authors: Zhao Yang, Jia-Qi Chen, Tian-Jie Liu, Yu-Le Chen, Zhen-Kun Ma, Yi-Zeng Fan, Zi-Xi Wang, Shan Xu, Ke Wang, Xin-Yang Wang, Lei Li, Hong-Jun Xie
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Asian Journal of Andrology
Subjects:
androgen receptor; circrna; exosome; prostate cancer
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2024;volume=26;issue=2;spage=195;epage=204;aulast=

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http://www.ajandrology.com/article.asp?issn=1008-682X;year=2024;volume=26;issue=2;spage=195;epage=204;aulast=

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