Commonalities Between ARDS, Pulmonary Fibrosis and COVID-19: The Potential of Autotaxin as a Therapeutic Target

Commonalities Between ARDS, Pulmonary Fibrosis and COVID-19: The Potential of Autotaxin as a Therapeutic Target

Severe COVID-19 is characterized by acute respiratory distress syndrome (ARDS)-like hyperinflammation and endothelial dysfunction, that can lead to respiratory and multi organ failure and death. Interstitial lung diseases (ILD) and pulmonary fibrosis confer an increased risk for severe disease, whil...

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Bibliographic Details
Main Authors: Konstantinos Ntatsoulis, Theodoros Karampitsakos, Eliza Tsitoura, Elli-Anna Stylianaki, Alexios N. Matralis, Argyrios Tzouvelekis, Katerina Antoniou, Vassilis Aidinis
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Immunology
Subjects:
COVID-19
ARDS
pulmonary fibrosis
Autotaxin
lysophosphatidic acid
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.687397/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.687397/full

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