Relationship between Adsorption and Toxicity of Nephrotoxic Drugs in Microphysiological Systems (MPS)

Relationship between Adsorption and Toxicity of Nephrotoxic Drugs in Microphysiological Systems (MPS)

Microphysiological systems (MPS) are an emerging technology for next-generation drug screening in non-clinical tests. Microphysiological systems are microfluidic devices that reconstitute the physiological functions of a human organ using a three-dimensional in vivo-mimicking microenvironment. In th...

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Bibliographic Details
Main Authors: Ryohei Ueno, Masahiro Kuninori, Takumi Sumi, Ramin Banan Sadeghian, Yuji Takata, Azusa Iguchi, Masahiro Tsuda, Fumiyoshi Yamashita, Kentaro Ichikawa, Ryuji Yokokawa
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Micromachines
Subjects:
microphysiological system (MPS)
cyclo-olefin polymer (COP)
nephrotoxicity
drug adsorption
drug screening
Online Access:https://www.mdpi.com/2072-666X/14/4/761

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https://www.mdpi.com/2072-666X/14/4/761

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