Evolution of major histocompatibility complex class I and class II genes in the brown bear

Evolution of major histocompatibility complex class I and class II genes in the brown bear

<p>Abstract</p> <p>Background</p> <p>Major histocompatibility complex (MHC) proteins constitute an essential component of the vertebrate immune response, and are coded by the most polymorphic of the vertebrate genes. Here, we investigated sequence variation and evolutio...

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Bibliographic Details
Main Authors: Kuduk Katarzyna, Babik Wiesław, Bojarska Katarzyna, Śliwińska Ewa B, Kindberg Jonas, Taberlet Pierre, Swenson Jon E, Radwan Jacek
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Evolutionary Biology
Subjects:
Positive selection
Antigen binding sites
MHC gene expression
Phylogenetic analysis
Orthology
<it>Ursidae</it>
Online Access:http://www.biomedcentral.com/1471-2148/12/197

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http://www.biomedcentral.com/1471-2148/12/197

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