Contributions of Epstein–Barr Nuclear Antigen 1 (EBNA1) to Cell Immortalization and Survival

Epstein–Barr virus (EBV) immortalizes host cells as part of its latent mode of infection. As a result of this ability to promote cell proliferation and survival, EBV infection contributes to the development of several kinds of B-cell lymphomas and epithelial tumours. The EBV Epstein–Barr nuclear ant...

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Bibliographic Details
Main Author: Lori Frappier
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/4/9/1537