Contributions of Epstein–Barr Nuclear Antigen 1 (EBNA1) to Cell Immortalization and Survival
Epstein–Barr virus (EBV) immortalizes host cells as part of its latent mode of infection. As a result of this ability to promote cell proliferation and survival, EBV infection contributes to the development of several kinds of B-cell lymphomas and epithelial tumours. The EBV Epstein–Barr nuclear ant...
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Format: | Article |
Language: | English |
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MDPI AG
2012-09-01
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Series: | Viruses |
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Online Access: | http://www.mdpi.com/1999-4915/4/9/1537 |