Enteric glia cells attenuate cytomix-induced intestinal epithelial barrier breakdown.

BACKGROUND: Intestinal barrier failure may lead to systemic inflammation and distant organ injury in patients following severe injury. Enteric glia cells (EGCs) have been shown to play an important role in maintaining gut barrier integrity through secretion of S-Nitrosoglutathione (GSNO). We have re...

Full description

Bibliographic Details
Main Authors: Gerald A Cheadle, Todd W Costantini, Nicole Lopez, Vishal Bansal, Brian P Eliceiri, Raul Coimbra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3698076?pdf=render