Burst firing is required for induction of Hebbian LTP at lateral perforant path to hippocampal granule cell synapses

Burst firing is required for induction of Hebbian LTP at lateral perforant path to hippocampal granule cell synapses

Abstract High frequency burst firing is critical in summation of back-propagating action potentials (APs) in dendrites, which may greatly depolarize dendritic membrane potential. The physiological significance of burst firings of hippocampal dentate GCs in synaptic plasticity remains unknown. We fou...

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Bibliographic Details
Main Authors: Yoonsub Kim, Sooyun Kim, Won-Kyung Ho, Suk-Ho Lee
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Molecular Brain
Subjects:
Dentate gyrus
Granule cell
Burst firing
Perforant pathway
Long-term potentiation
Calcium channel
Online Access:https://doi.org/10.1186/s13041-023-01034-w

Internet

https://doi.org/10.1186/s13041-023-01034-w

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