A Review of the Repair of DNA Double Strand Breaks in the Development of Oral Cancer

A Review of the Repair of DNA Double Strand Breaks in the Development of Oral Cancer

We explore the possibility that defects in genes associated with the response and repair of DNA double strand breaks predispose oral potentially malignant disorders (OPMD) to undergo malignant transformation to oral squamous cell carcinoma (OSCC). Defects in the homologous recombination/Fanconi anem...

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Bibliographic Details
Main Authors: Stephen S. Prime, Piotr Darski, Keith D. Hunter, Nicola Cirillo, E. Kenneth Parkinson
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:International Journal of Molecular Sciences
Subjects:
oral cancer development
DNA repair
double strand breaks
homologous recombination
Fanconi anemia
non-homologous end joining
Online Access:https://www.mdpi.com/1422-0067/25/7/4092

Internet

https://www.mdpi.com/1422-0067/25/7/4092

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