Synergistic effects of MFG-E8 and whey protein on mitigating d-galactose-induced sarcopenia through PI3K/AKT/PGC-1α and MAPK/ERK signaling pathways

Synergistic effects of MFG-E8 and whey protein on mitigating d-galactose-induced sarcopenia through PI3K/AKT/PGC-1α and MAPK/ERK signaling pathways

ABSTRACT: Milk fat globule epidermal growth factor 8 (MFG-E8) and whey protein have emerged as promising bionutrient supplements for enhancing skeletal muscle mass and function. In the present study, aging-related sarcopenia rat model was employed to elucidate the effects of the combined administrat...

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Bibliographic Details
Main Authors: He Li, Kaifang Guan, Rongchun Wang, Aihua Zhu, Ying Ma
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Journal of Dairy Science
Subjects:
sarcopenia
MFG-E8
whey protein
PI3K/Akt/PGC-1α signal pathway
mitochondria function
Online Access:http://www.sciencedirect.com/science/article/pii/S0022030223006136

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http://www.sciencedirect.com/science/article/pii/S0022030223006136

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