Differential Ire1 determines loser cell fate in tumor-suppressive cell competition

Summary: Tumor-suppressive cell competition (TSCC) is a conserved surveillance mechanism in which neighboring cells actively eliminate oncogenic cells. Despite overwhelming studies showing that the unfolded protein response (UPR) is dysregulated in various tumors, it remains debatable whether the UP...

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Bibliographic Details
Main Authors: Jiadong Zheng, Yifan Guo, Changyi Shi, Shuai Yang, Wenyan Xu, Xianjue Ma
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723013153