SYNTHESIS OF BENDAMUSTINE HYDROCHLORIDE IN FLOW MICROREACTOR

The possibility and prospects of carrying out the chlorination step in the scheme for the synthesis of bendamustine hydrochloride were investigated. The advantages and prospects of the process in the flow microreactor are shown. The conditions for conducting the process in the flow microreactor unde...

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Bibliographic Details
Main Authors: A. Moldavsky, A. M. Yurakov, M. B. Supurghibekov, P. I. Elagin, B. Yu. Lalaev, I. A. Fridman
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/510