FEAST: A flow cytometry-based toolkit for interrogating microglial engulfment of synaptic and myelin proteins

Abstract Although engulfment is a hallmark of microglia function, fully validated platforms that facilitate high-throughput quantification of this process are lacking. Here, we present FEAST (Flow cytometric Engulfment Assay for Specific Target proteins), which enables interrogation of in vivo engul...

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Bibliographic Details
Main Authors: Lasse Dissing-Olesen, Alec J. Walker, Qian Feng, Helena J. Barr, Alicia C. Walker, Lili Xie, Daniel K. Wilton, Indrani Das, Larry I. Benowitz, Beth Stevens
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41448-7