Bovine natural antibody IgM inhibits the binding of human norovirus protruding domain to its HBGA receptors

Human norovirus (HuNoV) is the primary viral pathogen that causes acute gastroenteritis (AGE) in humans. The protruding (P) domain of HuNoV interacts with cell surface histo‐blood group antigens (HBGAs) to initiate infection. Owing to the lack of an effective in vitro culture method and a robust ani...

Full description

Bibliographic Details
Main Authors: Qi Han, Zhaolei Xue, Ming Tan, Likai Wang, Huiling Chen, Ran Zhang
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.13450