Defining Reprogramming Checkpoints from Single-Cell Analyses of Induced Pluripotency

Defining Reprogramming Checkpoints from Single-Cell Analyses of Induced Pluripotency

Summary: Elucidating the mechanism of reprogramming is confounded by heterogeneity due to the low efficiency and differential kinetics of obtaining induced pluripotent stem cells (iPSCs) from somatic cells. Therefore, we increased the efficiency with a combination of epigenomic modifiers and signali...

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Bibliographic Details
Main Authors: Khoa A. Tran, Stefan J. Pietrzak, Nur Zafirah Zaidan, Alireza Fotuhi Siahpirani, Sunnie Grace McCalla, Amber S. Zhou, Gopal Iyer, Sushmita Roy, Rupa Sridharan
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719305297

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http://www.sciencedirect.com/science/article/pii/S2211124719305297

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