Engineering of Human Skeletal Muscle With an Autologous Deposited Extracellular Matrix

Adult skeletal muscle progenitor cells can be embedded in an extracellular matrix (ECM) and tissue-engineered to form bio-artificial muscles (BAMs), composed of aligned post-mitotic myofibers. The ECM proteins which have been used most commonly are collagen type I and fibrin. Fibrin allows for in vi...

Full description

Bibliographic Details
Main Authors: Lieven Thorrez, Katherine DiSano, Janet Shansky, Herman Vandenburgh
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01076/full