Dysfunction of Glutamatergic Synaptic Transmission in Depression: Focus on AMPA Receptor Trafficking

Pharmacological and anatomical evidence suggests that abnormal glutamatergic neurotransmission may be associated with the pathophysiology of depression. Compounds that act as NMDA receptor antagonists may be a potential treatment for depression, notably the rapid-acting agent ketamine. The rapid-act...

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Bibliographic Details
Main Authors: Jin-Gang He, Hai-Yun Zhou, Fang Wang, Jian-Guo Chen
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Biological Psychiatry Global Open Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667174322000222