A unique dual acyltransferase system shared in the polyketide chain initiation of kidamycinone and rubiflavinone biosynthesis

The pluramycin family of natural products has diverse substituents at the C2 position, which are closely related to their biological activity. Therefore, it is important to understand the biosynthesis of C2 substituents. In this study, we describe the biosynthesis of C2 moieties in Streptomyces sp....

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Bibliographic Details
Main Authors: Kyung Taek Heo, Byeongsan Lee, Gwi Ja Hwang, Beomcheol Park, Jun-Pil Jang, Bang Yeon Hwang, Jae-Hyuk Jang, Young-Soo Hong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1274358/full