Voltammetric Sensor Based on SeO<sub>2</sub> Nanoparticles and Surfactants for Indigo Carmine Determination
Indigo carmine is a widely used colorant in the food and pharmaceutical industry a high concentration of which can lead to a wide range of negative effects on human health. Therefore, colorant contents have to be strictly controlled. SeO<sub>2</sub>-nanoparticle-modified glassy carbon el...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-04-01
|
| Series: | Sensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1424-8220/22/9/3224 |
| _version_ | 1827671453032513536 |
|---|---|
| author | Liya Kavieva Guzel Ziyatdinova |
| author_facet | Liya Kavieva Guzel Ziyatdinova |
| author_sort | Liya Kavieva |
| collection | DOAJ |
| description | Indigo carmine is a widely used colorant in the food and pharmaceutical industry a high concentration of which can lead to a wide range of negative effects on human health. Therefore, colorant contents have to be strictly controlled. SeO<sub>2</sub>-nanoparticle-modified glassy carbon electrodes (GCE) have been developed as a voltammetric sensor for indigo carmine. Various types and concentrations of surfactants have been used as reagents for the stabilization of SeO<sub>2</sub> nanoparticle dispersions and as electrode surface co-modifiers. An amount of 1.0 mM cationic cetylpyridinium bromide (CPB) provides the best response of the indigo carmine on the modified electrode. The electrodes were characterized by cyclic voltammetry, chronoamperometry, and electrochemical impedance spectroscopy (EIS). SeO<sub>2</sub> nanoparticle–CPB-modified electrodes show 4.2-fold higher electroactive area vs. GCE as well as a dramatic 5043-fold decrease in the electron transfer resistance indicating effectivity of the modifier developed. The surface-controlled electrooxidation of indigo carmine proceeds irreversibly (α<sub>a</sub> = 0.46) with the participation of two electrons and two protons. A linear dynamic range of 0.025–1.0 and 1.0–10 µM of indigo carmine were obtained with the detection and quantification limits of 4.3 and 14.3 nM, respectively. The practical applicability of the sensor was successfully shown on the pharmaceutical dosage forms. |
| first_indexed | 2024-03-10T03:43:08Z |
| format | Article |
| id | doaj.art-8e6c24fa061c4c56a80a7f9ef2c5b8e0 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T03:43:08Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-8e6c24fa061c4c56a80a7f9ef2c5b8e02023-11-23T09:15:18ZengMDPI AGSensors1424-82202022-04-01229322410.3390/s22093224Voltammetric Sensor Based on SeO<sub>2</sub> Nanoparticles and Surfactants for Indigo Carmine DeterminationLiya Kavieva0Guzel Ziyatdinova1Analytical Chemistry Department, Kazan Federal University, Kremleyevskaya 18, 420008 Kazan, RussiaAnalytical Chemistry Department, Kazan Federal University, Kremleyevskaya 18, 420008 Kazan, RussiaIndigo carmine is a widely used colorant in the food and pharmaceutical industry a high concentration of which can lead to a wide range of negative effects on human health. Therefore, colorant contents have to be strictly controlled. SeO<sub>2</sub>-nanoparticle-modified glassy carbon electrodes (GCE) have been developed as a voltammetric sensor for indigo carmine. Various types and concentrations of surfactants have been used as reagents for the stabilization of SeO<sub>2</sub> nanoparticle dispersions and as electrode surface co-modifiers. An amount of 1.0 mM cationic cetylpyridinium bromide (CPB) provides the best response of the indigo carmine on the modified electrode. The electrodes were characterized by cyclic voltammetry, chronoamperometry, and electrochemical impedance spectroscopy (EIS). SeO<sub>2</sub> nanoparticle–CPB-modified electrodes show 4.2-fold higher electroactive area vs. GCE as well as a dramatic 5043-fold decrease in the electron transfer resistance indicating effectivity of the modifier developed. The surface-controlled electrooxidation of indigo carmine proceeds irreversibly (α<sub>a</sub> = 0.46) with the participation of two electrons and two protons. A linear dynamic range of 0.025–1.0 and 1.0–10 µM of indigo carmine were obtained with the detection and quantification limits of 4.3 and 14.3 nM, respectively. The practical applicability of the sensor was successfully shown on the pharmaceutical dosage forms.https://www.mdpi.com/1424-8220/22/9/3224nanoparticlessurfactantselectrochemical sensorsvoltammetrycolorantsindigo carmine |
| spellingShingle | Liya Kavieva Guzel Ziyatdinova Voltammetric Sensor Based on SeO<sub>2</sub> Nanoparticles and Surfactants for Indigo Carmine Determination Sensors nanoparticles surfactants electrochemical sensors voltammetry colorants indigo carmine |
| title | Voltammetric Sensor Based on SeO<sub>2</sub> Nanoparticles and Surfactants for Indigo Carmine Determination |
| title_full | Voltammetric Sensor Based on SeO<sub>2</sub> Nanoparticles and Surfactants for Indigo Carmine Determination |
| title_fullStr | Voltammetric Sensor Based on SeO<sub>2</sub> Nanoparticles and Surfactants for Indigo Carmine Determination |
| title_full_unstemmed | Voltammetric Sensor Based on SeO<sub>2</sub> Nanoparticles and Surfactants for Indigo Carmine Determination |
| title_short | Voltammetric Sensor Based on SeO<sub>2</sub> Nanoparticles and Surfactants for Indigo Carmine Determination |
| title_sort | voltammetric sensor based on seo sub 2 sub nanoparticles and surfactants for indigo carmine determination |
| topic | nanoparticles surfactants electrochemical sensors voltammetry colorants indigo carmine |
| url | https://www.mdpi.com/1424-8220/22/9/3224 |
| work_keys_str_mv | AT liyakavieva voltammetricsensorbasedonseosub2subnanoparticlesandsurfactantsforindigocarminedetermination AT guzelziyatdinova voltammetricsensorbasedonseosub2subnanoparticlesandsurfactantsforindigocarminedetermination |