Molecular architecture of the Gαi-bound TRPC5 ion channel

Molecular architecture of the Gαi-bound TRPC5 ion channel

Abstract G-protein coupled receptors (GPCRs) and ion channels serve as key molecular switches through which extracellular stimuli are transformed into intracellular effects, and it has long been postulated that ion channels are direct effector molecules of the alpha subunit of G-proteins (Gα). Howev...

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Bibliographic Details
Main Authors: Jongdae Won, Jinsung Kim, Hyeongseop Jeong, Jinhyeong Kim, Shasha Feng, Byeongseok Jeong, Misun Kwak, Juyeon Ko, Wonpil Im, Insuk So, Hyung Ho Lee
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-38281-3

Internet

https://doi.org/10.1038/s41467-023-38281-3

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