Nuclear receptor RXRα binds the precursor of miR-103 to inhibit its maturation

Nuclear receptor RXRα binds the precursor of miR-103 to inhibit its maturation

Abstract Background The maturation of microRNAs (miRNAs) successively undergoes Drosha, Dicer, and Argonaute ˗mediated processing, however, the intricate regulations of the individual miRNA maturation are largely unknown. Retinoid x receptor alpha (RXRα) belongs to nuclear receptors that regulate ge...

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Bibliographic Details
Main Authors: Xiaohong Ye, Yun Yang, Jiayue Yao, Mo Wang, Yixin Liu, Guobin Xie, Zhiping Zeng, Xiao-kun Zhang, Hu Zhou
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Biology
Subjects:
Nuclear receptor
RXRα
microRNA
Precursor microRNA
microRNA biogenesis
miR-103
Online Access:https://doi.org/10.1186/s12915-023-01701-3

Internet

https://doi.org/10.1186/s12915-023-01701-3

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