Hypoxia downregulated miR-4521 suppresses gastric carcinoma progression through regulation of IGF2 and FOXM1

Abstract Background MicroRNAs (miRNAs) show considerable promise as therapeutic agents to improve tumor treatment, as they have been revealed as crucial modulators in tumor progression. However, our understanding of their roles in gastric carcinoma (GC) metastasis is limited. Here, we aimed to ident...

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Bibliographic Details
Main Authors: Shan Xing, Zhi Tian, Wenying Zheng, Wenjuan Yang, Nan Du, Yixue Gu, Jiang Yin, Hao Liu, Xiaoting Jia, Donglan Huang, Wanli Liu, Min Deng
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Molecular Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12943-020-01295-2