Use of a Novel DNA-Loaded Alginate-Calcium Carbonate Biopolymer Surrogate to Study the Engulfment of Legionella pneumophila by Acanthamoeba polyphaga in Water Systems

Use of a Novel DNA-Loaded Alginate-Calcium Carbonate Biopolymer Surrogate to Study the Engulfment of Legionella pneumophila by Acanthamoeba polyphaga in Water Systems

ABSTRACT The engulfment of Legionella pneumophila by free-living amoebae (FLA) in engineered water systems (EWS) enhances L. pneumophila persistence and provides a vehicle for rapid replication and increased public health risk. Despite numerous legionellosis outbreaks worldwide, effective tools for...

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Bibliographic Details
Main Authors: Sujani Ariyadasa, Craig Billington, Mohamed Shaheen, Nicholas J. Ashbolt, Conan Fee, Liping Pang
Format: Article
Language:English
Published: American Society for Microbiology 2022-08-01
Series:Microbiology Spectrum
Subjects:
amoeba
Legionella pneumophila
public health
surrogate
waterborne pathogens
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02210-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.02210-22

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