Xeroderma Pigmentosum Complementation Group C (XPC): Emerging Roles in Non-Dermatologic Malignancies

Xeroderma Pigmentosum Complementation Group C (XPC): Emerging Roles in Non-Dermatologic Malignancies

Xeroderma pigmentosum complementation group C (XPC) is a DNA damage recognition protein essential for initiation of global-genomic nucleotide excision repair (GG-NER). Humans carrying germline mutations in the XPC gene exhibit strong susceptibility to skin cancer due to defective removal via GG-NER...

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Detalles Bibliográficos
Autores principales: Nawar Al Nasrallah, Benjamin M. Wiese, Catherine R. Sears
Formato: Artículo
Lenguaje:English
Publicado: Frontiers Media S.A. 2022-04-01
Colección:Frontiers in Oncology
Materias:
nucleotide excision repair (NER)
base excision repair (BER)
lung cancer
biomarker
bladder cancer
chemotherapy
Acceso en línea:https://www.frontiersin.org/articles/10.3389/fonc.2022.846965/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.846965/full

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