Studies on metal–organic framework (MOF) nanomedicine preparations of sildenafil for the future treatment of pulmonary arterial hypertension

Abstract Pulmonary arterial hypertension (PAH) is an incurable disease, although symptoms are treated with a range of dilator drugs. Despite their clinical benefits, these drugs are limited by systemic side-effects. It is, therefore, increasingly recognised that using controlled drug-release nanofor...

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Bibliographic Details
Main Authors: Nura A. Mohamed, Haissam Abou-Saleh, Yu Kameno, Isra Marei, Gilberto de Nucci, Blerina Ahmetaj-Shala, Fisnik Shala, Nicholas S. Kirkby, Lewis Jennings, Dana E. Al-Ansari, Robert P. Davies, Paul D. Lickiss, Jane A. Mitchell
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83423-6