Mechanisms that minimize retinal impact of apolipoprotein E absence[S]

Mechanisms that minimize retinal impact of apolipoprotein E absence[S]

Apolipoprotein E (APOE) is a component of lipid-transporting particles and a recognition ligand for receptors, which bind these particles. The APOE isoform ε2 is a risk factor for age-related macular degeneration; nevertheless, APOE absence in humans and mice does not significantly affect the retina...

Full description

Bibliographic Details
Main Authors: Aicha Saadane, Alexey Petrov, Natalia Mast, Nicole El-Darzi, Tung Dao, Ahab Alnemri, Ying Song, Joshua L. Dunaief, Irina A. Pikuleva
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Journal of Lipid Research
Subjects:
cholesterol
retina
lipoproteins
iron
cytoskeleton
vesicular traffic
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520341626

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520341626

Similar Items