A Genome Wide Study of Copy Number Variation Associated with Nasopharyngeal Carcinoma in Malaysian Chinese Identifies CNVs at 11q14.3 and 6p21.3 as Candidate Loci.

BACKGROUND:Nasopharyngeal carcinoma (NPC) is a neoplasm of the epithelial lining of the nasopharynx. Despite various reports linking genomic variants to NPC predisposition, very few reports were done on copy number variations (CNV). CNV is an inherent structural variation that has been found to be i...

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Bibliographic Details
Main Authors: Joyce Siew Yong Low, Yoon Ming Chin, Taisei Mushiroda, Michiaki Kubo, Gopala Krishnan Govindasamy, Kin Choo Pua, Yoke Yeow Yap, Lee Fah Yap, Selva Kumar Subramaniam, Cheng Ai Ong, Tee Yong Tan, Alan Soo Beng Khoo, Malaysian NPC Study Group, Ching Ching Ng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4701378?pdf=render