Synthesis, characterization and hepatoprotective effect of silymarin phytosome nanoparticles on ethanol-induced hepatotoxicity in rats

Introduction: Silymarin proved to be a beneficial herbal medicine against many hepatic disorders such as alcoholic liver disease (ALD). However, its application is restricted due to its low bioavailability and consequently decreased efficacy. We herein used a nano-based approach known as "phyto...

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Main Authors: Arezoo Gohari Mahmoudabad, Fatemeh Gheybi, Mohsen Mehrabi, Alireza Masoudi, Zeinab Mobasher, Hamid Vahedi, Anneh Mohammad Gharravi, Fatemeh Sadat Bitaraf, Seyed Mahdi Rezayat Sorkhabadi
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2023-07-01
Series:BioImpacts
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Online Access:https://bi.tbzmed.ac.ir/PDF/bi-13-301.pdf