Toxicity evaluation of 6-mercaptopurine-Chitosan nanoparticles in rats
Background: The 6-mercaptopurine (6-MP) is an effective immunosuppressant and anti-cancer drug. However, the usage of 6-MP is limited due to its well-known side effects, such as myelotoxicity and hepato-renal toxicity. To curtail the potential toxic effects, we have used chitosan as a natural biodeg...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
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Series: | Saudi Pharmaceutical Journal |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1319016419301598 |