Intergenerational association of gut microbiota and metabolism with perinatal folate metabolism and neural tube defects

Summary: Disorders of folic acid metabolism during pregnancy lead to fetal neural tube defects (NTDs). However, the mechanisms still require further investigation. Here, we aim to analyze the brain metabolic profiles of 30 NTDs and 30 healthy fetuses. Our results indicated that low-folate diet durin...

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Bibliographic Details
Main Authors: Shan Wang, Xuejia He, Yi Wang, Yubing Zeng, Pei Pei, Xiaojun Zhan, Min Zhang, Ting Zhang
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223015912