Steric shielding of surface epitopes and impaired immune recognition induced by the ebola virus glycoprotein.
Many viruses alter expression of proteins on the surface of infected cells including molecules important for immune recognition, such as the major histocompatibility complex (MHC) class I and II molecules. Virus-induced downregulation of surface proteins has been observed to occur by a variety of me...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-09-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2936550?pdf=render |