Implication of platelets and complement C3 as link between innate immunity and tubulointerstitial injury in renal vasculitis with MPO-ANCA seropositivity

Implication of platelets and complement C3 as link between innate immunity and tubulointerstitial injury in renal vasculitis with MPO-ANCA seropositivity

IntroductionAntineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a potentially life-threatening systemic small-vessel vasculitis that is characterized by pauci-immune glomerulonephritis, depicting in turn a major denominator of AAV mortality. It is well established that AAV pati...

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Bibliographic Details
Main Authors: Eva Baier, Désirée Tampe, Ingmar Alexander Kluge, Samy Hakroush, Björn Tampe
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
innate immunity
platelets
complement system
complement C3
ANCA-associated renal vasculitis
MPO-ANCA
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1054457/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1054457/full

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