In vivo antileishmanial action of Ir-(COD)-pentamidine tetraphenylborate on Leishmania donovani and Leishmania major mouse models

lr-(COD)-pentamidine tetraphenylborate which has previously been studied on promastigote forms of Leishmania, was investigated for its antileishmanial properties compared with pentamidine used as reference compound. In vitro, the iridium complex had the same IC50 value on intracellular forms of Leis...

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Detalhes bibliográficos
Main Authors: Loiseau P.M., Mbongo N., Bories C., Boulard Y., Craciunescu D.G.
Formato: Artigo
Idioma:English
Publicado em: EDP Sciences 2000-06-01
Colecção:Parasite
Assuntos:
Acesso em linha:http://dx.doi.org/10.1051/parasite/2000072103