Pharmacokinetic/pharmacodynamic (PK/PD) simulation for dosage optimization of colistin and sitafloxacin, alone and in combination, against carbapenem-, multidrug-, and colistin-resistant Acinetobacter baumannii

To the best of our knowledge, to date, no study has investigated the optimal dosage regimens of either colistin or sitafloxacin against drug-resistant Acinetobacter baumannii (A. baumannii) infections by using specific parameters. In the current study, we aimed to explore the optimal dosage regimens...

ver descrição completa

Detalhes bibliográficos
Principais autores: Vipavee Rodjun, Preecha Montakantikul, Jantana Houngsaitong, Kamonchanok Jitaree, Wichit Nosoongnoen
Formato: Artigo
Idioma:English
Publicado em: Frontiers Media S.A. 2023-11-01
coleção:Frontiers in Microbiology
Assuntos:
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1275909/full