Impaired VEGF Signaling in Lungs with Hypoplastic Esophageal Atresia and Effects on Branching Morphogenesis

Impaired VEGF Signaling in Lungs with Hypoplastic Esophageal Atresia and Effects on Branching Morphogenesis

Background/Aims: Patients with esophageal atresia (EA) and tracheoesophageal fistula (TEF) often suffer chronic respiratory tract disease. We previously reported that primary lung maldevelopment caused by deficient branching of embryonal airways in experimental EA-TEF was induced by Adriamycin. In t...

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Bibliographic Details
Main Authors: Xiaomei Liu, Caixia Liu, Tie Ma, Yisheng Jiao, Jianing Miao, Linlin Gao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
VEGF
Flt-1
Esophageal atresia
Fetal lung development
Branching
Online Access:http://www.karger.com/Article/FullText/445632

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http://www.karger.com/Article/FullText/445632

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