Genetic variants in FBN-1 and risk for thoracic aortic aneurysm and dissection.

Genetic variants in FBN-1 and risk for thoracic aortic aneurysm and dissection.

A recent genome wide association study (GWAS) by LeMaire et al. found that two single nucleotide polymorphisms (SNPs), rs2118181 and rs10519177 in the FBN-1 gene (encoding Fibrillin-1), were associated with thoracic aortic dissection (TAD), non-dissecting thoracic aortic aneurysm (TAA), and thoracic...

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Bibliographic Details
Main Authors: Olga A Iakoubova, Carmen H Tong, Charles M Rowland, May M Luke, Veronica E Garcia, Joseph J Catanese, Remo M Moomiaie, Peter Sotonyi, Gyorgy Ascady, Demitrios Nikas, Panagiotis Dedelias, Maryann Tranquilli, John A Elefteriades
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3990573?pdf=render

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http://europepmc.org/articles/PMC3990573?pdf=render

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