Identification of cancer-specific cell surface targets for CAR-T cell therapy
Abstract One should identify appropriate cell surface targets to develop new CAR-T cells. Currently, lineage-specific antigens such as CD19 or B cell maturation antigen (BCMA) are being used as targets for CAR-T cells. However, in most cancers, lineage-specific antigens cannot be used as targets bec...
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| Format: | Article |
| Language: | English |
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BMC
2024-03-01
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| Series: | Inflammation and Regeneration |
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| Online Access: | https://doi.org/10.1186/s41232-024-00329-2 |