Analysis of the early response to spinal cord injury identified a key role for mTORC1 signaling in the activation of neural stem progenitor cells

Abstract Xenopus laevis are able to regenerate the spinal cord during larvae stages through the activation of neural stem progenitor cells (NSPCs). Here we use high-resolution expression profiling to characterize the early transcriptome changes induced after spinal cord injury, aiming to identify th...

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Bibliographic Details
Main Authors: Johany Peñailillo, Miriam Palacios, Constanza Mounieres, Rosana Muñoz, Paula G. Slater, Elena De Domenico, Ilya Patrushev, Mike Gilchrist, Juan Larraín
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-021-00179-3