Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43

Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43

Generation of oligodendrocytes in the adult brain enables both adaptive changes in neural circuits and regeneration of myelin sheaths destroyed by injury, disease, and normal aging. This transformation of oligodendrocyte precursor cells (OPCs) into myelinating oligodendrocytes requires processing of...

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Bibliographic Details
Main Authors: Dongeun Heo, Jonathan P Ling, Gian C Molina-Castro, Abraham J Langseth, Ari Waisman, Klaus-Armin Nave, Wiebke Möbius, Phil C Wong, Dwight E Bergles
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-03-01
Series:eLife
Subjects:
oligodendrocyte
myelin
ALS
TDP-43
mRNA
progenitor
Online Access:https://elifesciences.org/articles/75230

Internet

https://elifesciences.org/articles/75230

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