The semaphorin 3A/neuropilin-1 pathway promotes clonogenic growth of glioblastoma via activation of TGF-β signaling
Glioblastoma (GBM) is the most lethal brain cancer with a dismal prognosis. Stem-like GBM cells (GSCs) are a major driver of GBM propagation and recurrence; thus, understanding the molecular mechanisms that promote GSCs may lead to effective therapeutic approaches. Through in vitro clonogenic growth...
Үндсэн зохиолчид: | , , , , , , , , , , , , , , , , , |
---|---|
Формат: | Өгүүллэг |
Хэл сонгох: | English |
Хэвлэсэн: |
American Society for Clinical investigation
2023-11-01
|
Цуврал: | JCI Insight |
Нөхцлүүд: | |
Онлайн хандалт: | https://doi.org/10.1172/jci.insight.167049 |