Thrombin increases the expression of cholesterol 25-hydroxylase in rat astrocytes after spinal cord injury

Thrombin increases the expression of cholesterol 25-hydroxylase in rat astrocytes after spinal cord injury

Astrocytes are important cellular centers of cholesterol synthesis and metabolism that help maintain normal physiological function at the organism level. Spinal cord injury results in aberrant cholesterol metabolism by astrocytes and excessive production of oxysterols, which have profound effects on...

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Bibliographic Details
Main Authors: Chen Chen, Huiyuan Ji, Nan Jiang, Yingjie Wang, Yue Zhou, Zhenjie Zhu, Yuming Hu, Yongjun Wang, Aihong Li, Aisong Guo
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Neural Regeneration Research
Subjects:
25-hydroxycholesterol; astrocyte; chemotaxis; cholesterol metabolism; cholesterol-25-hydroxylase; lipid homeostasis; macrophage; par1; spinal cord injury; thrombin
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=6;spage=1339;epage=1346;aulast=Chen

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=6;spage=1339;epage=1346;aulast=Chen

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