Genetic variants in LGALS3 are related to lower galectin-3 serum levels and clinical outcomes in systemic sclerosis patients: A case-control study

Genetic variants in LGALS3 are related to lower galectin-3 serum levels and clinical outcomes in systemic sclerosis patients: A case-control study

Introduction Systemic sclerosis (SSc) is a rare complex disease characterized by vascular damage, autoimmunity, and extensive skin and internal organs fibrosis. Galectin-3 (Gal-3) is encoded by gene LGALS3 (Lectin, Galactoside-Binding, Soluble, 3; 14q22.3) and it has been reported to play a central...

Full description

Bibliographic Details
Main Authors: Eudes Gustavo Constantino Cunha, Camilla Albertina Dantas de Lima, Kamila de Melo Vilar, Marcelo Francisco de Nóbrega, Anderson Rodrigues de Almeida, Michelly Cristiny Pereira, Andréa Tavares Dantas, Rafaela Silva Guimarães Gonçalves, Moacyr Jesus Barreto de Melo Rêgo, Angela Luzia Branco Pinto Duarte, Maira Galdino da Rocha Pitta
Format: Article
Language:English
Published: Taylor & Francis Group 2021-05-01
Series:Autoimmunity
Subjects:
scleroderma
lgals3
galectin-3
glycobiology
polymorphism
Online Access:http://dx.doi.org/10.1080/08916934.2021.1919881

Internet

http://dx.doi.org/10.1080/08916934.2021.1919881

Similar Items