Peptides derived from MARCKS block coagulation complex assembly on phosphatidylserine

Abstract Blood coagulation involves activation of platelets and coagulation factors. At the interface of these two processes resides the lipid phosphatidylserine. Activated platelets expose phosphatidylserine on their outer membrane leaflet and activated clotting factors assemble into enzymatically...

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Bibliographic Details
Main Authors: Noah Kastelowitz, Ryo Tamura, Abimbola Onasoga, Timothy J. Stalker, Ormacinda R. White, Peter N. Brown, Gary L. Brodsky, Lawrence F. Brass, Brian R. Branchford, Jorge Di Paola, Hang Yin
Format: Article
Language:English
Published: Nature Portfolio 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-04494-y