MUC16 stimulates neutrophils to an inflammatory and immunosuppressive phenotype in ovarian cancer
Abstract Background MUC16 (CA125) is a commonly used tumor marker for ovarian cancer screening and reported to be an immunosuppressive factor by acting on the sialic acid-binding immunoglobulin-like lectin-9 (Siglec-9) on the surface of natural killer cells (NK cells), B cells, and monocytes. Howeve...
Príomhchruthaitheoirí: | , , , , , , , , , , , |
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Formáid: | Alt |
Teanga: | English |
Foilsithe / Cruthaithe: |
BMC
2023-08-01
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Sraith: | Journal of Ovarian Research |
Ábhair: | |
Rochtain ar líne: | https://doi.org/10.1186/s13048-023-01207-0 |