Effects of Modulation of the Hedgehog and Notch Signaling Pathways on Osteoblast Differentiation Induced by Titanium with Nanotopography

Background: The events of bone formation and osteoblast/titanium (Ti) interactions may be affected by Hedgehog and Notch signalling pathways. Herein, we investigated the effects of modulation of these signalling pathways on osteoblast differentiation caused by the nanostructured Ti (Ti-Nano) generat...

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Main Authors: Paola Gomes Souza, Leticia Faustino Adolpho, Helena Bacha Lopes, Denise Weffort, Alann Thaffarell Portilho Souza, Fabiola Singaretti Oliveira, Adalberto Luiz Rosa, Marcio Mateus Beloti
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Journal of Functional Biomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4983/14/2/79