USP14 exhibits high expression levels in hepatocellular carcinoma and plays a crucial role in promoting the growth of liver cancer cells through the HK2/AKT/P62 axis

USP14 exhibits high expression levels in hepatocellular carcinoma and plays a crucial role in promoting the growth of liver cancer cells through the HK2/AKT/P62 axis

Abstract Background Hepatocellular carcinoma (HCC) is a common malignant tumor with strong invasiveness and poor prognosis. Previous studies have demonstrated the significant role of USP14 in various solid tumors. However, the role of USP14 in the regulation of HCC development and progression remain...

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Bibliographic Details
Main Authors: Nannan Zhang, Hui Zhang, Xiaobing Yang, Qiang Xue, Quhui Wang, Renan Chang, Lirong Zhu, Zhong Chen, Xiancheng Liu
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Cancer
Subjects:
Hepatocellular carcinoma
Double quinone enzymes
USP14
Online Access:https://doi.org/10.1186/s12885-024-12009-y

Internet

https://doi.org/10.1186/s12885-024-12009-y

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