Minocycline and risperidone prevent microglia activation and rescue behavioral deficits induced by neonatal intrahippocampal injection of lipopolysaccharide in rats.

<h4>Background</h4>Various signs of activation of microglia have been reported in schizophrenia, and it is hypothesized that microglia activation is closely associated with the neuropathology of schizophrenia.<h4>Methods</h4>Neonatal intrahippocampal injection of lipopolysacc...

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Bibliographic Details
Main Authors: Furong Zhu, Yingjun Zheng, Yu-qiang Ding, Yong Liu, Xianghui Zhang, Renrong Wu, Xiaofeng Guo, Jingping Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0093966&type=printable