Extracellular vesicles from synovial fluid-derived mesenchymal stem cells confer chondroprotective effects on in vitro and in vivo osteoarthritic chondrocytes

Extracellular vesicles from synovial fluid-derived mesenchymal stem cells confer chondroprotective effects on in vitro and in vivo osteoarthritic chondrocytes

Introduction: Extracellular vesicles (EVs) released by mesenchymal stem cells (MSCs) are theorized to mediate cartilage regeneration through paracrine actions. It is hypothesized that EVs derived from synovial fluid MSCs (SF-MSCs) will promote anabolic gene expressions and decrease catabolic markers...

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Bibliographic Details
Main Authors: Haixiang Liang, Dan Li, Eric V. Neufeld, Michael J. Sayegh, Adam Kiridly, Pablo Palacios, Henintsoa Fanjaniaina Andriamifidy, Pooja Swami, Kenneth R. Zaslav, Nicholas A. Sgaglione, Daniel A. Grande
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Journal of Cartilage & Joint Preservation
Subjects:
Cartilage
Extracellular vesicles
Osteoarthritis
Stem cells
Synovial fluid
Online Access:http://www.sciencedirect.com/science/article/pii/S2667254523000525

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http://www.sciencedirect.com/science/article/pii/S2667254523000525

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