Population pharmacokinetics of ivermectin after mass drug administration in lymphatic filariasis endemic communities of Tanzania

Population pharmacokinetics of ivermectin after mass drug administration in lymphatic filariasis endemic communities of Tanzania

Abstract Ivermectin (IVM) is a drug of choice used with albendazole for mass drug administration (MDA) to halt transmission of lymphatic filariasis. We investigated IVM pharmacokinetic (PK) variability for its dose optimization during MDA. PK samples were collected at 0, 2, 4, and 6 h from individua...

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Bibliographic Details
Main Authors: Adam M. Fimbo, Eulambius M. Mlugu, Eliford Ngaimisi Kitabi, Gerald S. Kulwa, Mohammed A. Iwodyah, Rajabu Hussein Mnkugwe, Peter P. Kunambi, Alpha Malishee, Appolinary A. R. Kamuhabwa, Omary M. Minzi, Eleni Aklillu
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.13038

Internet

https://doi.org/10.1002/psp4.13038

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