Evolution and dynamics of regulatory architectures controlling polymyxin B resistance in enteric bacteria.

Complex genetic networks consist of structural modules that determine the levels and timing of a cellular response. While the functional properties of the regulatory architectures that make up these modules have been extensively studied, the evolutionary history of regulatory architectures has remai...

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Bibliographic Details
Main Authors: Alexander Y Mitrophanov, Mollie W Jewett, Tricia J Hadley, Eduardo A Groisman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2565834?pdf=render